Ibrexafungerp

Ibrexafungerp: A novel antifungal

Ibrexafungerp, an enfumafungin derivative, belongs to a new family called triterpenoid antifungals.This is a new class called “-fungerp”. This antifungal class inhibits glucan synthetase required for fungal cell wall synthesis. One of the major antifungal class echinocandins also acts by this mechanism and has been used since 2001. Echinocandins, however, have poor bioavailability and are […]