Amphotericin B

Amphotericin B is a polyene antibiotic discovered in 1953 from the bacteria Streptomyces nodosus, in the Orinoco basin in Venezuela. Its name is derived from its amphoteric property, being able to react to both acid and base. It is insoluble at normal pH; hence it is available as a buffered colloidal solution, with sodium deoxycholate…

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Infection associated with chronic granulomatous disease (CGD)

Introduction CGD is a rare inherited immunodeficiency disorder where the NADPH oxidase in the phagocytic cells is absent or malfunctioning. Most CGDs are inherited as X linked, while the rest are autosomal recessive. Phagocytes, like neutrophils and monocytes, in the absence of NADPH oxidase, cannot kill the ingested pathogens due to the lack of oxidative burst. As a result,…

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yersinia

Summary of SMI: ID 21: Yersinia

Interactive Yersinia Species Identification Guide 🔬 Yersinia Species Identification Guide Comprehensive laboratory identification and characterization of Yersinia species Overview Species Laboratory Process Safety Media Summary 🦠 Genus Yersinia Overview 📊 Taxonomy Family: Enterobacteriaceae Species: 17 recognized species + 2 subspecies Type species: Yersinia pestis Pathogenic species: Y. pestis, Y. pseudotuberculosis, Y. enterocolitica 🧬 General Characteristics…

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Leptospira

Leptospira spp.

This is from a presentation. The pictures were my slides. Feel free to download them if you wish. Leptospirosis, a zoonosis, is caused by a pathogenic Spirochaeta of the genus Leptospira.The name is derived from the Greek leptos (thin) and the Latin spira (coiled). Leptospirosis is a multisystem disease first described by Albert Weil in…

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