Introduction There are various types of E coli that live in the environment and our intestines. Although most live inside our bowel harmlessly and even be beneficial, some E coli may cause infection, like UTI, bacteraemia, gastroenteritis etc. The E coli causing gastroenteritis could be divided into six phenotypes – Shiga toxin-producing E. coli (STEC) [or EHEC/VTEC]…
An IMG’s Perspective by Dr Chidi Onwukwe (2018) I decided to sit for the FRCPath part 1 in MMV sometime in 2018. I didn’t have a timeframe to work with as it was basically a loose decision made in a rare moment of inspiration. The first window of opportunity came in November/December 2018 in the…
Brucellosis is a zoonotic infection transmitted to humans from animals (cattle, goats, sheep) via The UK is a non-endemic country. Most brucella cases in the UK are imported cases with links to Mediterranean or Middle Eastern countries. However, Brucella is also endemic in Central Asia, China, South Asia, sub-Saharan Africa, and some parts of Middle and…
Introduction Candida auris is a pathogen that has emerged as a global threat in recent years. It is the first human pathogenic fungus subject to international health alerts. The reason behind these concerns are – Public Health England reported in 2017 that almost all the C auris in the UK are fluconazole-resistant. There is also…
Members of the microregistrar moodle programme took part in a poll. See the results.
Ibrexafungerp, an enfumafungin derivative, belongs to a new family called triterpenoid antifungals.This is a new class called “-fungerp”. This antifungal class inhibits glucan synthetase required for fungal cell wall synthesis. One of the major antifungal class echinocandins also acts by this mechanism and has been used since 2001. Echinocandins, however, have poor bioavailability and are…
Patients with an absent or dysfunctional spleen (AoDS) are at increased risk of infection, especially with capsulated bacteria. What are the organisms that can cause infection in patients with AoDS? Prevention of infection – vaccines, antibiotic prophylaxis Antibiotic What is the risk of sepsis?The risk of death from sepsis is 600 times more than the…
Please note this is a study note, keeping the exam in mind. This is not a guideline and should not be used for that purpose. It is not for clinical use either. You should contact your doctor for clinical advice. Blood donation screening ORGANISM MANDATORY TEST ADDITIONAL TEST HIV anti-HIV 1+2 or HIV 1+2 Ag/Ab…
Specimens Throat swab, posterior pharyngeal swab, nasopharyngeal swab, pharyngeal washings, pus aspirate, oropharyngeal swab, throat gargle. Why To investigate upper respiratory tract infection – Pharyngitis, Tonsillitis, Epiglottitis, and Laryngitis. Condition Target organisms Pharyngitis(sore throat) 1. Viral (commonest),2. Group A Streptococcus/ Streptococcus pyogenes,3. Group C/G Streptococcus – Streptococcus dysgalactiae subspecies equisimilis,4. Streptococcus anginosus group,5. Corynebacterium –…
