Turicella otitidis

The Bacteria: Turicella otitidis is an anaerobic, non-motile, pleomorphic, gram-positive bacillus – similar to coryneform but longer.It produces a convex whitish/cream-coloured non-haemolytic colony.CAMP test positiveDNase and Catalase positive.Oxidase negative. It is often misidentified as Corynebacterium by some commercial systems. See the Pinterest images here: Pathogenicity – Otitis media Turicella is a commensal of the external…

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Capnocytophaga spp.

Capnocytophaga genus belongs to the family Flavobacteriaceae.There are >9 species of Capnocytophaga, which can be divided into two groups – resident of human mouth flora and dog/cat mouth flora. Species found in the human oral cavity C. gingivalis, C. granulosa, C. haemolytica, C. leadbetteri, C. ochracea and C. sputigena Species found in dog/cat oral cavity C. canimorsus and C. cynodegmi Risk factors…

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Tigecycline

Daptomycin

Class: Cyclic lipopeptideSource: Streptomyces roseosporusDiscovered: 1980s; approved for use in 2003 (FDA)Molecular weight: 1620 DA. Mechanism of action: The Daptomycin (DAP) combines with Calcium ions to form a positively charged complex that attaches to the bacterial cell membrane (preferably at the nascent septa). This attachment depends upon the presence of phospholipid phosphatidylglycerol (PG). After attachment, DAP forms…

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Cefalexin

Nature of the antibiotic Mechanism of action Cefalexin, like other beta-lactams, binds to the penicillin-binding protein (PBP) and prevents peptidoglycan synthesis. It prevents the formation of new cell walls and maintenance of the cell wall leading to autolysis of the bacteria due to osmotic pressure. Mechanism of resistance PK/PD and other properties Indication (cefalexin is…

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