Microorganisms are only listed as “intrinsically resistant” to an agent (or group of agents) when a vast majority of wild-type isolates exhibit MIC values that are so high that the agent should not be considered for either therapy or clinical susceptibility testing (EUCAST). Enterobacterales & Aeromonas Enterobacterales and Aeromonas are intrinsically resistant to benzylpenicillin, glycopeptides,…
Nature of the antibiotic Mechanism of action Cefalexin, like other beta-lactams, binds to the penicillin-binding protein (PBP) and prevents peptidoglycan synthesis. It prevents the formation of new cell walls and maintenance of the cell wall leading to autolysis of the bacteria due to osmotic pressure. Mechanism of resistance PK/PD and other properties Indication (cefalexin is…
Fusidic acid was discovered in Copenhagen, Denmark and introduced to clinical practice in the 1960s.It was derived from a fungus, Fusidium coccineum. Fusidic acid has a structural similarity with the steroid molecule. You can see in the picture the molecular structure is similar to prednisolone. For this reason, it is called a steroid antibiotic. It also…
This is an effort to preserve some wonderful materials I used as a trainee. This website is not being updated anymore and may disappear in the future. I have no intention of infringing the copyright – if antimicrobe.org wishes me to remove the material, please get in touch with me. Updated June, 2013 Kevin J….
This is an effort to preserve some wonderful materials I used as a trainee. This website is not being updated anymore and may disappear in the future. I have no intention of infringing the copyright – if antimicrobe.org wishes me to remove the material, please get in touch with me. Updated March, 2009 Sally A…
William Riebel, M.D. GENERAL DESCRIPTION Microbiology Guided Medline Search Lactococci are gram-positive cocci that arrange in pairs and short chains with a tendency to an ovoid shape in the direction of the chain. They grow in catalase-negative, non-pigmented, generally non-hemolytic colonies on blood agar, similar to oral streptococci. Previously classified as group N streptococci,…
Baltimore classification – classification of viruses based on how they produce their mRNA.
For FRCPath Microbiology, I consider the fungi highlighted in yellow are must-read. Grey highlighted ones – if you have time.
