Necrotising fasciitis
Necrotising fasciitis (NF): It is an infection of the subcutaneous tissue/fat and fascia of the skin. It spreads rapidly along the fascial plane. Muscles are less commonly affected/ affected later in the disease due to better blood supply. Classification Types Organism Note Type 1 – polymicrobial/synergistic Aerobic and anaerobic bacteria Often derived from gut/bowel Type…
Yellow fever vaccine: study note
Vaccine: Coadministration with other vaccines It can be co-administered (on different limbs /the same limb 2.5 cm apart) with other inactivated and most live vaccines, except MMR, which should be given 28 days apart. If yellow fever and MMR were given together due to the immediate need for protection, repeat vaccine doses should be considered individually….
Types of studies
Research Category Types Experimental Studies – Randomized Controlled Trials (RCT)– Laboratory Experiments– Field Experiments– Quasi-experimental Studies– Pre-test/Post-test Design Observational Studies – Cohort Studies– Case-Control Studies– Cross-sectional Studies– Longitudinal Studies– Ecological Studies Qualitative Studies – Ethnographic Research– Phenomenological Studies– Grounded Theory Studies– Case Studies– Narrative Research– Focus Groups Mixed Methods – Sequential Mixed Methods– Concurrent Mixed…
Trainee experience: Tips for part 1 FRCPath Microbiology
One of my trainees, who joined us as a year 1 infection trainee, recently passed part 1 FRCPath. I worked closely with him as a clinical supervisor. I asked him what tips he would give other trainees preparing for part 1. I think talking to you and looking at your Microregistrar and Facebook FRCPath blogs…
Actinomyces spp
Understanding Actinomyces: The Ray Fungus That’s Actually a Bacterium ⚠️ DISCLAIMER: This content is for academic and educational purposes only. Always consult current medical guidelines and seek professional medical advice for clinical decisions. 🦠 What is Actinomyces? + 🔬 Taxonomy Despite its name meaning “ray fungus,” Actinomyces is actually a bacteria that reproduces by binary…
Antibiotic – intrinsic resistance
Enterobacterales & Aeromonas Enterobacterales and Aeromonas are intrinsically resistant to benzylpenicillin, glycopeptides, lipoglycopeptides, fusidic acid, macrolides (Except Azithromycin, effective for typhoid/paratyphoid fever and erythromycin for travellers’ diarrhoea), lincosamides, streptogramins, rifampicin, and oxazolidinones. Bacteria Beta-lactams Non-beta-lactams Klebsiella pneumonia complex,Klebsiella oxytocaRoultella sp.Citrobacter koseri,Citrobacter amalonaticus Amoxicillin, Ticarcillin Klebsiella aerogenes,Enterobacter cloacae complexCitrobacter freundiiHafnia alvei Amoxicillin, Coamoxiclav,1st generation cephalosporinsCefoxitin Serratia…
UK vaccination schedule (July 2025)
UK Immunisation Schedule Timeline UK Immunisation Schedule Timeline 8 weeks First vaccinations Diphtheria, tetanus, pertussis Polio, Hib, Hepatitis B Meningococcal group B Rotavirus 12 weeks Second round Diphtheria, tetanus, pertussis Polio, Hib, Hepatitis B MenB Rotavirus 16 weeks Third round Diphtheria, tetanus, pertussis Polio, Hib, Hepatitis B Pneumococcal (13 types) 1 year One year boosters…
Greenbook notes: Pertussis (Whooping cough) vaccine
Pertussis vaccine Pertussis vaccine is only given as a part of a combined vaccine. Monovalent pertussis vaccines are not available. Vaccines are stored at +2˚C to +8˚C, protected from light. Excess heat – reduces potency and shelf-life.Excess cold/freezing – increases reactogenicity and loss of potency; it may also cause hairline cracks on the ampoule leading…
SMI (note): Investigation of swabs from the skin and superficial soft tissue infection
Specimen Advice for the users: Safety Processing Gram stain – usually not done unless deep-seated pus from a normally sterile site Plate selection CONDITION PLATES All clinical conditions Blood agarCLED/MacConkey agar Wound swab Selective anaerobic agar with metronidazole disc Pus Fastidious anaerobic, cooked meat broth;then Subculture to blood agar. Cellulitis in childrenHuman bite Chocolate agar…