Rothia mucilaginosa

The Bacteria Rothia belongs to the family Micrococcaceae – the same family as Micrococcus spp., Stomatococcus spp. and Kocuria spp. There are 8 species of Rothia – but only Rothia dentocariosa and Rothia mucilaginosa has been associated with human disease. It is a member of the mouth and upper respiratory tract flora. Laboratory Infection Rothia…

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Dengue vaccine – Greenbook Summary

Vaccine Description and Composition “The dengue vaccination Qdenga® is a tetravalent live attenuated vaccine. It is produced in Vero cells by recombinant DNA technology and contains serotype-specific surface protein genes of the four dengue serotypes, engineered into a dengue type 2 backbone.” Storage and Presentation “Vaccines should be stored in the original packaging at +2C̊…

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Aspergillus niger

The Fungus: Identification: It initially forms white colonies with a yellow back, which quickly becomes black. Conidia is rough, brownish-black, biseriate, and covers the entire vesicle. A key feature in diagnosing A. niger infection is the presence of calcium oxalate crystals on pathological examination. The presence of crystals can be taken as an indication of A niger…

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Paracoccus Yeei

Paracoccus yeei is an aerobic Gram-negative coccobacilli typically found in soil and brine. It appears as diplococci and may have a visible vacuole – giving an “O” shaped appearance. It may under-decolourise and appear as Gram-positive cocci. It is oxidase-positive and confused with Moraxella/Neisseria. Identification can be made using automated systems like VITEK-2 GN, MALDI-ToF and DNA…

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Microregistrar moodlecloud update – Rhodotorula, AI, RAG and revision aid

I regularly ask MoodleCloud members what provides more value to them. From a recent poll, I found that microbiologists preparing for the FRCPath exam using Microregistrar Moodle find the Quick revision summary helpful. All moodle chapters in the next few months will be updated with a quick revision note (yellow box). With this, it will…

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Tigecycline

Daptomycin

Class: Cyclic lipopeptideSource: Streptomyces roseosporusDiscovered: 1980s; approved for use in 2003 (FDA)Molecular weight: 1620 DA. Mechanism of action: The Daptomycin (DAP) combines with Calcium ions to form a positively charged complex that attaches to the bacterial cell membrane (preferably at the nascent septa). This attachment depends upon the presence of phospholipid phosphatidylglycerol (PG). After attachment, DAP forms…

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Actinomyces spp

Understanding Actinomyces: The Ray Fungus That’s Actually a Bacterium ⚠️ DISCLAIMER: This content is for academic and educational purposes only. Always consult current medical guidelines and seek professional medical advice for clinical decisions. 🦠 What is Actinomyces? + 🔬 Taxonomy Despite its name meaning “ray fungus,” Actinomyces is actually a bacteria that reproduces by binary…

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