Neurobrucellosis

Brucellosis is a zoonotic infection transmitted to humans from animals (cattle, goats, sheep) via The UK is a non-endemic country. Most brucella cases in the UK are imported cases with links to Mediterranean or Middle Eastern countries. However, Brucella is also endemic in Central Asia, China, South Asia, sub-Saharan Africa, and some parts of Middle and…

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Enterococcus

Mechanism of resistance in Enterococcus

Enterococci are intrinsically resistant to many classes of antibiotics – like cephalosporins, Aminoglycoside (low-level resistance), macrolides, clindamycin, quinupristin-dalfopristin (E faecalis), Fusidic acid, Sulfonamide [EUCAST], which limits our options when we try to treat Enterococcal infections. Most clinical infections are caused by Enterococcus faecalis, followed by Enterococcus faecium.Other Enterococci occasionally isolated from the clinical specimen are…

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Norovirus

Epidemiology Norovirus is the most common cause of epidemic gastroenteritis worldwide. In the UK, norovirus outbreak is usually seen in the winter months. The virus Norovirus is a small non-enveloped RNA virus of the caliciviridae family. It has ten genogroups, but I, II and IV are primarily implicated in human infection. Genogroup II is most…

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PVL Staph aureus

Post for academic purposes only. It MUST NOT be used to make a clinical decision. For clinical advice, please discuss with your doctor. PVL Staphylococcus aureus Clinical Guide Clinical Guide for Diagnosis and Management In the UK, PVL genes are carried by < 2% of clinical S. aureus isolates 🔍 Clinical Features Recognize skin/soft tissue…

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