Aspergillus niger

The Fungus: Identification: It initially forms white colonies with a yellow back, which quickly becomes black. Conidia is rough, brownish-black, biseriate, and covers the entire vesicle. A key feature in diagnosing A. niger infection is the presence of calcium oxalate crystals on pathological examination. The presence of crystals can be taken as an indication of A niger…

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Leptospira

Leptospira spp.

This is from a presentation. The pictures were my slides. Feel free to download them if you wish. Leptospirosis, a zoonosis, is caused by a pathogenic Spirochaeta of the genus Leptospira.The name is derived from the Greek leptos (thin) and the Latin spira (coiled). Leptospirosis is a multisystem disease first described by Albert Weil in…

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Adeno

Adenovirus

Introduction For high-resolution images, scroll to the bottom of the page Human adenovirus has 7 species based on their haemagglutination character.Each species was divided into serotypes based on neutralisation (e.g. A- 12,18, 31). At present, genotyping is being used to classify Adenovirus.Different species of human adenovirus have different tissue tropism. Species Tissue tropism A GI, respiratory,…

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Microregistrar moodlecloud update – Rhodotorula, AI, RAG and revision aid

I regularly ask MoodleCloud members what provides more value to them. From a recent poll, I found that microbiologists preparing for the FRCPath exam using Microregistrar Moodle find the Quick revision summary helpful. All moodle chapters in the next few months will be updated with a quick revision note (yellow box). With this, it will…

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Rothia mucilaginosa

The Bacteria Rothia belongs to the family Micrococcaceae – the same family as Micrococcus spp., Stomatococcus spp. and Kocuria spp. There are 8 species of Rothia – but only Rothia dentocariosa and Rothia mucilaginosa has been associated with human disease. It is a member of the mouth and upper respiratory tract flora. Laboratory Infection Rothia…

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SMI (note): Investigation of swabs from the skin and superficial soft tissue infection

Specimen Advice for the users: Safety Processing Gram stain – usually not done unless deep-seated pus from a normally sterile site Plate selection CONDITION PLATES All clinical conditions Blood agarCLED/MacConkey agar Wound swab Selective anaerobic agar with metronidazole disc Pus Fastidious anaerobic, cooked meat broth;then Subculture to blood agar. Cellulitis in childrenHuman bite Chocolate agar…

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Antibiotic – intrinsic resistance

Enterobacterales & Aeromonas Enterobacterales and Aeromonas are intrinsically resistant to benzylpenicillin, glycopeptides, lipoglycopeptides, fusidic acid, macrolides (Except Azithromycin, effective for typhoid/paratyphoid fever and erythromycin for travellers’ diarrhoea), lincosamides, streptogramins, rifampicin, and oxazolidinones. Bacteria Beta-lactams Non-beta-lactams Klebsiella pneumonia complex,Klebsiella oxytocaRoultella sp.Citrobacter koseri,Citrobacter amalonaticus Amoxicillin, Ticarcillin Klebsiella aerogenes,Enterobacter cloacae complexCitrobacter freundiiHafnia alvei Amoxicillin, Coamoxiclav,1st generation cephalosporinsCefoxitin Serratia…

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