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Microregistrar Infection Newsletter · Saturday 7 November 2026
WHO DON625: Bundibugyo Ebola at 10,668 / 5,198 in DRC — UK doctor in care at the Royal Free.
WHO Disease Outbreak News 2026-DON625 (published 6 Nov 2026, evening GMT) updates Bundibugyo virus disease (BVD) since DON622 (23 Oct). As of 3 Nov: 10,668 confirmed cases and 5,198 confirmed deaths in the Democratic Republic of the Congo (crude CFR 48.7%) across 67 health zones in eight provinces; active transmission in 51 zones. WHO notes geographic expansion with sustained high-level transmission; +964 confirmed cases / +511 deaths since the prior DON. No new cases from Kenya or Nigeria since DON622. Switzerland and the United Kingdom have medically evacuated confirmed cases among their citizens.
UKHSA primary confirmation (news 5 Nov 19:47 GMT; blog same day): a UK medical doctor who worked on the DRC response tested positive and was medevaced to the high-level isolation unit at the Royal Free Hospital, London. Risk to the UK public remains low (contact/bodily-fluid transmission; HCID IPC). Yesterday’s issue flagged this only via CIDRAP/Guardian/FluTrackers — now primary. Ebola was eligible to lead (no Ebola lead 1–6 Nov; last Ebola lead 24 Oct).
Check before quoting: quote WHO DON625 (to 3 Nov: 10,668 / 5,198) separately from UKHSA OUM week 44 (to 1 Nov: 10,532 / 5,126) and from any CDC/CIDRAP “today” tallies — do not merge. Compilation cut-off early morning — see metadata. Journals omitted (Journal Watch).
Counted without journals (Journal Watch owns journals from 5 Nov 2026). Agency tally includes DON625, DON624, UKHSA UK Ebola news/blog, MHRA Co-Amoxiclav Class 4 (5 Nov), COVID-19 vaccination HCP information page updated 6 Nov, PHS/PHW/HPSC week-44 respiratory reports, and in-window CIDRAP measles / AMS items. Flu week 45 and UK SMI V 5 are carried as context, not re-counted as new.
Also today
The other headlines from today’s issue. Each card links to its source and to the full summary.
DON624: yellow fever continues in WHO African Region
Published 6 Nov: 67 confirmed cases / 18 deaths in nine countries (1 Jan–12 Oct 2026). Transmission concentrated in parts of West Africa.
US measles 2026 total tops 5,100 (CDC via CIDRAP)
CIDRAP 6 Nov: 5,182 confirmed; +330 this week; 13th straight week with a triple-digit rise. PA +61 (1,487 YTD) with a further death noted in the piece.
Wales week 44: influenza now circulating
PHW ARI report week 44 (ending 1 Nov): confirmed influenza in sentinel GPs up and indicators suggest influenza is now circulating; RSV low intensity; COVID case numbers stabilised.
Scotland week 44: flu rising; COVID medium
PHS 5 Nov report (data 26 Oct–1 Nov): influenza activity continued to rise but lab-confirmed cases still low overall; influenza hospital admissions 207 (from 178). COVID medium and rising; RSV baseline.
Class 4 defect: Sandoz Co-Amoxiclav oral suspension
EL(26)A/46 published 5 Nov. Defect notification for Co-Amoxiclav powder for oral suspension 250/62.5 mg/5 mL — check the alert before clinical action.
COVID-19 vaccination HCP information page updated 6 Nov
GOV.UK page dateModified 6 Nov 13:41 GMT. Programme information for healthcare practitioners; change-note detail not fully extracted in the shortened window.
What we could not confirm
Shortened morning window (cut-off 06:15 Europe/London, not 08:10). Ebola tallies still conflict across WHO DON625 (to 3 Nov), UKHSA OUM week 44 (to 1 Nov) and secondary CDC/CIDRAP figures. Infectious Disease Advisor “Weekly Handoff” (memory: Gmail 1a1b12bfeb4aed4b) not found in microregistrar2021 or microregistrar inboxes. CDC HAN Access Denied / 403. ECDC CDTR still week 42. ERVISS landing last dated content seen as 9 Oct. Journals intentionally omitted.
Microregistrar Moodle update
Read from the MoodleCloud Google Sheet Index tab (“Whats new?” column) on the morning of 7 Nov. No new dated rows since yesterday’s issue; top rows remain the two 4 Nov entries.
Staphylococcus capitis and NRCS-A
Staphylococcus saprophyticus
C. diphtheriae & C. ulcerans Interactive
Still listed below the 4 Nov entries. Moodle ›
Greenbook vaccine part 1 revision
Unchanged. Moodle ›
Watched pages
Core UK watched pages re-checked on the morning of 7 Nov (before 06:15), plus the nine user-approved Friday-scan sources (now daily). Material new items are expanded in Agencies.
Flu/COVID surveillance: still week 45 (5 Nov) — no week 46 yet. Carried from yesterday; not re-led. Week 45 › · Collection ›
Syndromic surveillance: still week 44 (5 Nov); next due 12 Nov. Week 44 ›
Outbreaks under monitoring: still week 44 (ending 1 Nov). Tallies superseded for lead purposes by WHO DON625 (to 3 Nov). Week 44 ›
HCID country risk: still last change note 5 Nov (Guinea, Hungary, Myanmar) — no newer timestamp this morning. HCID ›
Ebola / Marburg outbreak locations: page timestamp 5 Nov 15:30 GMT (same window as UK case / HCID). Locations ›
Bird flu (England): unchanged after Brigg AIV 2026/23 (public_updated still 4 Nov 19:59 GMT). Situation ›
Green Book / ch25: ch25 still 3 Nov 08:37 GMT; no newer chapter spotted. Collection ›
MHRA alerts: new Class 4 Co-Amoxiclav and Class 3 Tropicamide (both dated 5 Nov); FSN list still 26–30 Oct. Alerts ›
UK SMI / NICE / exams / measles England / HPR: no newer SMI issue, NICE infection guideline, exam notice, England measles epi update or HPR beyond issue 10 (29 Oct) in this run. UK SMI › · NICE ›
Friday-scan nine (all checked): PHS week 44 report (5 Nov); PHW week 44 PDF; NI respiratory page last reviewed 5 Nov (no new bulletin text extracted); HPSC Ireland integrated week 44 (5 Nov); ERVISS/ECDC — no newer summary than previously noted; EUCAST news newest retained items late Oct (voriconazole rationale 29 Oct; VetCAST consultation 28 Oct); SAPG — no new dated update in window; HIS news 6 Nov = members’ survey (not IPC guidance); PAHO — newest epi update still dengue/chikungunya 20 Oct (outside window as new lead).
Agencies & guidance
WHO, UKHSA, MHRA, devolved UK/Ireland respiratory surveillance, and CIDRAP items inside the window. Each card links to the primary page we used (CIDRAP marked secondary).
WHO / global outbreaks
Bundibugyo virus disease — DRC, Kenya and Nigeria (6 Nov 2026)
As of 3 Nov 2026: 10,668 confirmed cases and 5,198 deaths in DRC (CFR 48.7%); 2,881 recoveries. 67 health zones / 8 provinces; 51 zones with cases in the preceding 21 days. +964 confirmed / +511 deaths since DON622. Last 21 days: 1,463 new confirmed (Ituri 710, Nord Kivu 640, Haut-Uélé 77, Tshopo 31, Nord-Ubangi 5). Of 512 deaths since 21 Oct, 335 were in communities. No new Kenya or Nigeria cases since DON622. France and Uganda outbreaks controlled since August. WHO notes UK and Swiss medevacs of confirmed cases among citizens. Risk assessment under revision; advises against travel/trade restrictions based on available information.
Tally conflict: UKHSA OUM week 44 (to 1 Nov) was 10,532 / 5,126. Quote the source and date you mean.
Yellow fever — WHO African Region (6 Nov 2026)
Between 1 Jan and 12 Oct 2026: 67 confirmed cases including 18 deaths in nine countries — Burkina Faso, Cameroon, Central African Republic, Côte d’Ivoire, Ghana, Guinea, Liberia, Nigeria and Togo (list as stated in DON). Transmission continues with recent activity concentrated in parts of West Africa.
UKHSA / England
UK citizen returned from DRC for specialist Ebola care
GOV.UK news published 5 Nov 2026 19:47 GMT. A UK medical doctor working on the DRC Ebola response tested positive and was medically evacuated to the high-level isolation unit at the Royal Free Hospital, London. UKHSA (Dr Renu Bindra): risk to the wider public remains low; Ebola spreads by direct contact with symptomatic patients’ bodily fluids, not through the air. Companion UKHSA blog (5 Nov) and @UKHSA post (6 Nov ~10:57 GMT) align. This upgrades yesterday’s unverified press/CIDRAP claim to primary UKHSA confirmation.
Week 45 flu above baseline — unchanged since yesterday
No week 46 report yet. Reminder only: influenza above baseline with NHS briefing; positivity 7.6%; hospital admissions 2.83 per 100,000 (data to week 44).
COVID-19 vaccination programme: information for healthcare practitioners
Page Updated 6 November 2026 (dateModified 13:41 GMT). Applies to England. Shortened window: section-level delta vs prior version not fully re-diffed — open the page before changing practice.
Class 4: Sandoz Co-Amoxiclav oral suspension EL(26)A/46
Published 5 Nov (alongside a Class 3 Tropicamide eye-drops recall). Infection-relevant because Co-Amoxiclav is widely used; read the defect details and batch list on GOV.UK. FSN weekly list still ends 26–30 Oct.
Devolved UK / Ireland respiratory (Friday-scan sources)
Wales: influenza now circulating
Weekly ARI report week 44 (ending 1 Nov 2026). Headline: confirmed influenza in sentinel GPs increased and indicators suggest influenza is now circulating in Wales; RSV at low intensity; COVID case numbers stabilised in recent weeks; EuroMoMo “no excess” all-cause mortality in the most recent week.
Scotland viral respiratory report (5 Nov)
Data 26 Oct–1 Nov (ISO week 44). Syndromic indicators stable at baseline. Influenza activity continued to rise; lab-confirmed cases still low overall. CARI: influenza A positivity rose sharply in 0–4y (35.5% from 3.4%) and 5–14y (40.0% from 12.5%) over recent weeks. Influenza hospital admissions 207 (from 178; +16%), higher than the same point in the prior five seasons. COVID medium and rising; RSV stable at baseline. Next report due 12 Nov.
Ireland integrated respiratory bulletin week 44
Listed on HPSC integrated reports page as published 5 Nov 2026 (week 44). Large HTML bulletin retrieved; figures not fully re-digitised in the shortened window — open the bulletin for numbers.
Respiratory surveillance page last reviewed 5 Nov
PHA respiratory surveillance page shows last reviewed 5 Nov 2026. No separate new week-numbered bulletin text extracted beyond the standing page in this run.
Measles · US (secondary)
US 2026 total 5,182 — 13th straight triple-digit weekly rise
CIDRAP 6 Nov, citing CDC: 5,182 confirmed (+330 this week). 59% in children/teens; 96% unvaccinated or unknown status; 11% hospitalised. Only five states with no 2026 cases listed (AR, HI, MS, NV, NH). Pennsylvania +61 (1,487 YTD); piece notes another PA death (sixth PA fatality in the article’s wording) — verify against PA DOH before quoting deaths. Wisconsin infant death already covered yesterday from WI DHS primary.
ECDC / EUCAST / HIS / PAHO / SAPG
CDTR archive still week 42
Weeks 43–45 still missing. ERVISS ECDC landing shows older dating (9 Oct content seen); erviss.org retrieved but no new dated summary extracted this morning.
No newer clinical breakpoint tables in window
News page: voriconazole rationale v4.1 (29 Oct); VetCAST breakpoint tables public consultation (28 Oct). No 6–7 Nov breakpoint release.
6 Nov: Annual Members’ Survey
Healthcare Infection Society news item 6 Nov inviting members to complete the annual survey — not new IPC guidance. Operating theatre suites guidance (2026) remains on the guidelines-by-topic page.
Newest epi update still 20 Oct (dengue/chikungunya)
No newer epidemiological alert/update than 20 Oct 2026 spotted on the alerts landing this morning.
No new dated AMS update in window
Latest-updates index checked; no new November-dated prescribing guidance item identified in the shortened run.
CIDRAP (secondary)
CRE rising in medically vulnerable US paediatric patients
6 Nov CIDRAP summary of surveillance data showing an increase in carbapenem-resistant Enterobacterales infections in medically vulnerable children (secondary; underlying study not opened as a journal pick).
Quick takes: cholera DRC; Canada mRNA flu / flu-COVID vaccines; polio
6 Nov secondary round-up. Treat as a pointer — verify national regulator pages before quoting authorisations.
Carried (already reported 6 Nov — not new)
V 5 Laboratory diagnosis of hepatitis C virus (issue 8)
Still current; issued bulletin 5 Nov. No newer SMI this morning.
Two Bundibugyo candidates for Tumaini (4 Nov)
Still relevant context for DON625; not re-led.
On X
Saturday light check: agency and society accounts (UKHSA, ECDC, WHO, WHO/AFRO, CDC, MHRA, CIDRAP, IDSA, ESCMID) and FluTrackers posts on Ebola, H5N1 and measles, from 6 Nov ~08:00 GMT to this morning. Each item links to the post we read.
Agencies and societies
UKHSA: primary confirmation of UK Ebola medevac / Royal Free care; public risk remains low. @UKHSA › · Also MMR/mumps meningitis note @UKHSA ›; MenB eligibility RT.
CIDRAP: US measles >5,100 @CIDRAP ›; PA adult measles pattern @CIDRAP ›; paediatric CRE @CIDRAP ›; quick takes @CIDRAP ›
No new infection posts from ECDC, WHO, WHO/AFRO, MHRA, IDSA or ESCMID matched in this light agency search window after 6 Nov 08:00 GMT.
Outbreaks (relays)
Ebola: Kenya government relay via FluTrackers — no new cases for 18 days; 1 person still under treatment (unverified here against a Kenya MoH primary page). @FluTrackers ›
H5N1: multiple FluTrackers USDA/Canada/Mexico farm and wild-bird relays overnight — unverified against USDA/APHA primaries in this light run. England bird-flu situation page still unchanged after Brigg.
Measles: FluTrackers relay of further Cattaraugus County (NY) cases — unverified. @FluTrackers ›
Unverified: FluTrackers relays were not checked against primary government sources in this light run, except where we already have UKHSA/WHO/CIDRAP pages above.
What we could not confirm
We want you to know exactly where today’s issue has limits. Journals are intentionally out of remit (Journal Watch). Here are the 11 gaps we couldn’t close, plus reports that weren’t out yet.
| Source | Issue |
|---|---|
| Compilation window | Shortened morning cut-off 06:15 Europe/London (GMT) for 07:00 publication — not the nominal 08:10. Late-morning releases after cut-off are not in this issue. |
| Ebola tallies | WHO DON625 (to 3 Nov): 10,668 / 5,198. UKHSA OUM week 44 (to 1 Nov): 10,532 / 5,126. Secondary CDC/CIDRAP figures may differ again. Do not merge. |
| Mail Sorter / ID Advisor | Infectious Disease Advisor “Weekly Handoff” cited in memory (Gmail 1a1b12bfeb4aed4b) not found in microregistrar2021 or microregistrar searches this run. |
| HPSC week 44 | Bulletin HTML retrieved (~6 MB) but key indicator tables not fully re-digitised before cut-off. |
| COVID HCP page | Updated 6 Nov 13:41 GMT; section-level change list not fully extracted. |
| CDC | HAN archive Access Denied / 403 again. Travel notices page retrieved (Ebola Level 3/4 still listed) — no new November-dated notice text extracted beyond existing Ebola notices. |
| ECDC / ERVISS | CDTR still week 42; weeks 43–45 missing. ERVISS no new dated summary confirmed this morning. |
| PA measles deaths | CIDRAP notes a further PA death; not re-confirmed against PA DOH primary in this run. |
| X (light) | Saturday light check (2 searches). Relay accounts are secondary. |
| NI PHA | Page last reviewed 5 Nov; no separate new week bulletin body extracted. |
| Moodle / NICE / exams / SAPG | No new Moodle rows; no new NICE infection guideline, RCPath exam notice or SAPG November guidance item spotted in the shortened window. |
Not out yet
- UKHSA: week 46 flu/COVID-19 report; syndromic week 45 (due 12 Nov); next OUM after week 44; HCAI monthly to October 2026; next England measles epi update.
- ECDC: CDTR weeks 43–45 (overdue); fresher ERVISS summary.
- WHO: revised Ebola rapid risk assessment (DON625 says under revision); AFRO sitrep with reconciled tallies.
- CDC: HAN (blocked to us); reconciled national measles death tally vs state reports.
- PHS / PHW / HPSC / NI: week 45 respiratory reports (PHS next due 12 Nov).
Sources
What we checked for this issue. Every link in the issue was retrieved and checked during this run. Journals were not scanned (remit change 5 Nov 2026).
- Watched UK pages re-checked on the morning of 7 Nov, before 06:15 (flu/COVID collection, syndromic, OUM, HCID, Ebola/Marburg locations, bird flu England, Green Book/ch25, MHRA alerts, UK SMI, NICE, exams, measles collection, HPR vol 20, Salmonellaella collection)
- Microregistrar moodlecloud Google Sheet (Index tab), read directly through the Sheets connector — no new rows since 4 Nov
- WHO Disease Outbreak News API + DON625 / DON624 / DON623 pages
- UKHSA: UK Ebola GOV.UK news; UKHSA blog; COVID-19 vaccination HCP information page
- Mail (microregistrar2021@gmail.com): no new infection forward in window; ID Advisor Handoff not found; prior syndromic/SMI already used yesterday
- User-approved daily nine: Public Health Scotland respiratory + week 44 report; Public Health Wales week 44 ARI PDF; NI PHA respiratory surveillance; Ireland HPSC integrated week 44; ECDC ERVISS + erviss.org; EUCAST breakpoints + news; SAPG (+ latest updates); HIS guidelines + news; PAHO epidemiological alerts
- ECDC CDTR archive; CDC travel notices (HAN blocked)
- CIDRAP per-topic feeds (Ebola 64, measles 78, avian flu 49, AMS 48, influenza 69, HAI 81141, COVID-19 178636, pertussis 87, mpox 230556, C. auris 232685)
- X (Saturday light check): agency search + FluTrackers outbreak search over 6–7 Nov
- Live site baseline: microregistrar.com/newsletter/ and local 2026-11-06.html
Past issues
- Daily newsletter, 6 Nov 2026
- Daily newsletter, 5 Nov 2026
- Daily newsletter, 4 Nov 2026
- Daily newsletter, 3 Nov 2026
- Daily newsletter, 2 Nov 2026
- Daily newsletter, 1 Nov 2026
- Daily newsletter, 31 Oct 2026
- Daily newsletter, 30 Oct 2026
- Daily newsletter, 29 Oct 2026
- Daily newsletter, 28 Oct 2026
- Daily newsletter, 27 Oct 2026
- Daily newsletter, 26 Oct 2026
- Daily newsletter, 25 Oct 2026
- Daily newsletter, 24 Oct 2026
- Daily newsletter, 23 Oct 2026
- Daily newsletter, 22 Oct 2026
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- Daily newsletter, 19 Oct 2026
- Daily newsletter, 18 Oct 2026
- Daily newsletter, 17 Oct 2026
- Daily newsletter, 16 Oct 2026
- Daily newsletter, 15 Oct 2026
- Daily newsletter, 14 Oct 2026
- Daily newsletter, 13 Oct 2026
- Daily newsletter, 12 Oct 2026
- Daily newsletter, 11 Oct 2026
- Daily newsletter, 10 Oct 2026