Journal Watch

Medical Microbiology & Infection · 06/11/2026

Journal Watch

New papers from 27 core journals plus medRxiv preprints, 05 Nov – 06 Nov 2026, for FRCPath trainees and trainers.

16Papers
14PubMed
2Preprints
8Major articles
6Journals with papers
2UK-led

PubMed Entrez dates 5–6 Nov 2026 only; medRxiv infectious-disease preprints first published 4–6 Nov 2026 via the medRxiv API (Europe PMC returned none for that window; catch-up from preprint_pending_from 4 Nov). Papers already listed in prior issues are excluded. Summaries restate abstract text only; “not stated” means the record did not give it. Country is from the first author’s affiliation. Topic, study type, major-article section and FRCPath-relevance lines are automated labels. Preprints are not peer reviewed. No clinical advice is given.

Landmark studies0

None in this issue.

Cochrane reviews0

None in this issue.

Meta-analyses1

Meta-analysesBacteriaSystematic reviewPreprint

Vitamin D supplementation to prevent tuberculosis infection and disease: systematic review and individual participant data meta-analysis of randomised controlled trials

Journal medRxiv (preprint, not peer reviewed) · First author Jolliffe, D. A. · Country not stated · Study type Systematic review

Key findings (from abstract)

Four trials contributed IPD for 14,619 participants. Vitamin D did not reduce risk of incident tuberculosis infection (9,557 participants; aOR 0.97, 95% CI 0.81-1.18; p=0.79) or incident tuberculosis disease (14,533 participants; aOR 0.78, 95% CI 0.56-1.10; p=0.15). Vitamin D supplementation did not reduce the risk of incident tuberculosis infection or disease in the populations studied, either overall or within sub-groups. The 95% confidence interval of the effect estimate for prevention of tuberculosis disease remains compatible with a potentially important benefit, and further trials for this indication may be warranted.

FRCPath relevance

Bacteriology content relevant to FRCPath Part 1/2 clinical bacteriology and pathogen-specific management.

Systematic reviews0

None in this issue.

Narrative reviews1

Narrative reviewsVirusReviewUK

Combination antiviral treatment for a patient with lymphocytic choriomeningitis virus meningoencephalitis associated with bispecific antibody teclistamab therapy for myeloma.

Journal The Lancet Infectious Diseases · First author Maamari RG · Country United Kingdom · Study type Review

Key findings (from abstract)

The patient regained functional independence and returned to work, with only mild residual symptoms. In addition to reporting a novel occurrence of LCMV infection in a patient on teclistamab, the case highlights the presence of LCMV in the UK and the utility of metagenomic next-generation sequencing for pathogen identification in undiagnosed encephalitis. Finally, the case provides preliminary evidence supporting combination antiviral therapy in persistent LCMV infection.

FRCPath relevance

Clinical virology content relevant to FRCPath virology/infection curricula (diagnosis, epidemiology, management).

Other major articles6

Other major articlesInfection controlGenomic studyUK

The evolution of carbapenem-resistant Klebsiella pneumoniae in Greek intensive care units is driven by local carbapenemase acquisition, nationwide nosocomial spread and emerging resistance to novel antimicrobials.

Journal Journal of Infection · First author Baltas I · Country United Kingdom · Study type Genomic study

Key findings (from abstract)

All isolates produced carbapenemases: 48% KPC, 20% NDM, 4.4% VIM, 27.6% multi-carbapenemase producers. Resistance to carbapenems, fluoroquinolones, aminoglycosides, and co-trimoxazole exceeded 90%, except for amikacin (73.4%) and colistin (46.5%). In Greek ICUs, CR-Kp appears to emerge via local plasmid acquisition and then spread within and between hospitals. While aztreonam-avibactam and cefepime-zidebactam remain promising treatment options, resistance among multi-carbapenemase producers and diagnostic gaps (notably for VEB variants) are concerning.

FRCPath relevance

Infection prevention and control content relevant to FRCPath IPC and outbreak-management competencies.

Other major articlesVirusSurveillance studyEurope

Viral Aetiology of Lower Respiratory Tract Infections in Infants Attending Primary Care in Eastern Spain, 2023-2025.

Journal The Journal of Infectious Diseases · First author Marcello-Carloni L · Country Italy · Study type Surveillance study

Key findings (from abstract)

To describe seasonal patterns of respiratory viruses in infants presenting to primary care (PC) after the rollout of the RSV-immunisation programme in Spain, we analysed multiplex RT-PCR results from infants <1 year with lower respiratory tract infections (LRTIs) attending 57 PC centres in Valencia and Murcia across two seasons. Among the 307 infants, rhinovirus/enterovirus and RSV were the most common detections in both periods. hMPV, bocavirus, and influenza followed. Our findings highlight the importance of community-based surveillance systems for providing real-world evidence to inform future immunisation strategies.

FRCPath relevance

Clinical virology content relevant to FRCPath virology/infection curricula (diagnosis, epidemiology, management).

Other major articlesAMR/AMSSurveillance study

Linezolid Minimum Inhibitory Concentration Creep and Precision Dosing in Older Adults: a longitudinal surveillance and multicentre population pharmacokinetic study.

Journal Journal of Infection · First author Liu T · Country China · Study type Surveillance study

Key findings (from abstract)

Among 506 isolates, geometric mean minimum inhibitory concentration (MIC) increased from 1.587 to 1.796mg/L; the proportion at 2mg/L increased from 69.2% to 82.2%, whereas values ≤ 1mg/L decreased from 30.8% to 16.7%. Pharmacokinetic analysis included 406 patients and 1,032 samples; age and eGFR influenced clearance. Linezolid MICs shifted towards 2mg/L, while age and eGFR contributed to exposure variability. MIC-informed model-informed precision dosing, early therapeutic drug monitoring, and haematological monitoring may help balance efficacy and toxicity.

FRCPath relevance

AMR/antimicrobial stewardship content relevant to FRCPath antimicrobial therapy, susceptibility testing and AMS.

Other major articlesAMR/AMSSurveillance studyEurope

Diversity and host association of cfr-carrying plasmids of multidrug-resistant microorganisms from the Netherlands.

Journal International Journal of Antimicrobial Agents · First author Jansen TH · Country Netherlands · Study type Surveillance study

Key findings (from abstract)

Dutch plasmids linked to plasmids from China, Denmark, the United States, South-Korea, Germany and Poland. Across all Dutch plasmids, the cfr-gene was flanked by transposable elements. The diversity among cfr-carrying plasmids in unrelated Dutch surveillance isolates and their relatedness to plasmids from countries in different global regions suggest multiple independent introductions into the Netherlands, although horizontal dissemination by transposons may contribute to their spread.

FRCPath relevance

AMR/antimicrobial stewardship content relevant to FRCPath antimicrobial therapy, susceptibility testing and AMS.

Other major articlesVirusnot stated

Biological Sex as a Determinant of Neurological Outcomes During Zika Virus Infection.

Journal The Journal of Infectious Diseases · First author Mansour A · Country Canada · Study type not stated

Key findings (from abstract)

Given that many viral infections can lead to long-term neurological complications, it is crucial to understand how biological sex influences neuroinflammation. Using a mouse model of Zika virus infection, we find that males develop more severe clinical disease compared to females, despite comparable infectious viral loads. Our findings demonstrate that sexually dimorphic immune responses contribute to increased male susceptibility to virus-induced neuropathology.

FRCPath relevance

Clinical virology content relevant to FRCPath virology/infection curricula (diagnosis, epidemiology, management).

Other major articlesDiagnosticsSurveillance study

Anti-HCV signal-to-cutoff ratio for predicting hepatitis C viremia in a hospital-based population and genotype distribution: A five-year single-center study.

Journal Diagnostic Microbiology and Infectious Disease · First author Şanda ZS · Country not stated · Study type Surveillance study

Key findings (from abstract)

Of 337,030 anti-HCV tests, 1,434 (0.42%) were reactive, and all were tested for HCV-RNA. Of these, 363 (0.11%) were viremic. Anti-HCV S/CO ratios predict the presence of viremia but not its magnitude. Furthermore, genotype 1b predominated in older age groups, while genotypes 4 and 5 were more frequently observed among patients of Syrian nationality.

FRCPath relevance

Laboratory diagnostics content relevant to FRCPath test evaluation, laboratory methods and quality.

Bacteria2

BacteriaSystematic reviewPreprint

Vitamin D supplementation to prevent tuberculosis infection and disease: systematic review and individual participant data meta-analysis of randomised controlled trials

Journal medRxiv (preprint, not peer reviewed) · First author Jolliffe, D. A. · Country not stated · Study type Systematic review

Key findings (from abstract)

Four trials contributed IPD for 14,619 participants. Vitamin D did not reduce risk of incident tuberculosis infection (9,557 participants; aOR 0.97, 95% CI 0.81-1.18; p=0.79) or incident tuberculosis disease (14,533 participants; aOR 0.78, 95% CI 0.56-1.10; p=0.15). Vitamin D supplementation did not reduce the risk of incident tuberculosis infection or disease in the populations studied, either overall or within sub-groups. The 95% confidence interval of the effect estimate for prevention of tuberculosis disease remains compatible with a potentially important benefit, and further trials for this indication may be warranted.

FRCPath relevance

Bacteriology content relevant to FRCPath Part 1/2 clinical bacteriology and pathogen-specific management.

BacteriaProspective study

A parsimonious machine-learning model using routine laboratory data to differentiate nontuberculous mycobacterial disease from tuberculosis: Development and independent external validation.

Journal Diagnostic Microbiology and Infectious Disease · First author Zhang R · Country China · Study type Prospective study

Key findings (from abstract)

A post-hoc benchmark did not show an overall advantage for Extra Trees over other algorithms. Routine variables may help prioritize confirmatory testing, but the frozen threshold cannot support stand-alone diagnosis or exclusion of NTM. Prospective evaluation must verify patient-level measurement timing, reference diagnoses and clinical impact.

FRCPath relevance

Bacteriology content relevant to FRCPath Part 1/2 clinical bacteriology and pathogen-specific management.

Virus4

VirusReviewUK

Combination antiviral treatment for a patient with lymphocytic choriomeningitis virus meningoencephalitis associated with bispecific antibody teclistamab therapy for myeloma.

Journal The Lancet Infectious Diseases · First author Maamari RG · Country United Kingdom · Study type Review

Key findings (from abstract)

The patient regained functional independence and returned to work, with only mild residual symptoms. In addition to reporting a novel occurrence of LCMV infection in a patient on teclistamab, the case highlights the presence of LCMV in the UK and the utility of metagenomic next-generation sequencing for pathogen identification in undiagnosed encephalitis. Finally, the case provides preliminary evidence supporting combination antiviral therapy in persistent LCMV infection.

FRCPath relevance

Clinical virology content relevant to FRCPath virology/infection curricula (diagnosis, epidemiology, management).

VirusSurveillance studyEurope

Viral Aetiology of Lower Respiratory Tract Infections in Infants Attending Primary Care in Eastern Spain, 2023-2025.

Journal The Journal of Infectious Diseases · First author Marcello-Carloni L · Country Italy · Study type Surveillance study

Key findings (from abstract)

To describe seasonal patterns of respiratory viruses in infants presenting to primary care (PC) after the rollout of the RSV-immunisation programme in Spain, we analysed multiplex RT-PCR results from infants <1 year with lower respiratory tract infections (LRTIs) attending 57 PC centres in Valencia and Murcia across two seasons. Among the 307 infants, rhinovirus/enterovirus and RSV were the most common detections in both periods. hMPV, bocavirus, and influenza followed. Our findings highlight the importance of community-based surveillance systems for providing real-world evidence to inform future immunisation strategies.

FRCPath relevance

Clinical virology content relevant to FRCPath virology/infection curricula (diagnosis, epidemiology, management).

Virusnot stated

Biological Sex as a Determinant of Neurological Outcomes During Zika Virus Infection.

Journal The Journal of Infectious Diseases · First author Mansour A · Country Canada · Study type not stated

Key findings (from abstract)

Given that many viral infections can lead to long-term neurological complications, it is crucial to understand how biological sex influences neuroinflammation. Using a mouse model of Zika virus infection, we find that males develop more severe clinical disease compared to females, despite comparable infectious viral loads. Our findings demonstrate that sexually dimorphic immune responses contribute to increased male susceptibility to virus-induced neuropathology.

FRCPath relevance

Clinical virology content relevant to FRCPath virology/infection curricula (diagnosis, epidemiology, management).

Mycology0

No papers in this topic today.

Infection control1

Infection controlGenomic studyUK

The evolution of carbapenem-resistant Klebsiella pneumoniae in Greek intensive care units is driven by local carbapenemase acquisition, nationwide nosocomial spread and emerging resistance to novel antimicrobials.

Journal Journal of Infection · First author Baltas I · Country United Kingdom · Study type Genomic study

Key findings (from abstract)

All isolates produced carbapenemases: 48% KPC, 20% NDM, 4.4% VIM, 27.6% multi-carbapenemase producers. Resistance to carbapenems, fluoroquinolones, aminoglycosides, and co-trimoxazole exceeded 90%, except for amikacin (73.4%) and colistin (46.5%). In Greek ICUs, CR-Kp appears to emerge via local plasmid acquisition and then spread within and between hospitals. While aztreonam-avibactam and cefepime-zidebactam remain promising treatment options, resistance among multi-carbapenemase producers and diagnostic gaps (notably for VEB variants) are concerning.

FRCPath relevance

Infection prevention and control content relevant to FRCPath IPC and outbreak-management competencies.

AMR/AMS6

AMR/AMSSurveillance study

Linezolid Minimum Inhibitory Concentration Creep and Precision Dosing in Older Adults: a longitudinal surveillance and multicentre population pharmacokinetic study.

Journal Journal of Infection · First author Liu T · Country China · Study type Surveillance study

Key findings (from abstract)

Among 506 isolates, geometric mean minimum inhibitory concentration (MIC) increased from 1.587 to 1.796mg/L; the proportion at 2mg/L increased from 69.2% to 82.2%, whereas values ≤ 1mg/L decreased from 30.8% to 16.7%. Pharmacokinetic analysis included 406 patients and 1,032 samples; age and eGFR influenced clearance. Linezolid MICs shifted towards 2mg/L, while age and eGFR contributed to exposure variability. MIC-informed model-informed precision dosing, early therapeutic drug monitoring, and haematological monitoring may help balance efficacy and toxicity.

FRCPath relevance

AMR/antimicrobial stewardship content relevant to FRCPath antimicrobial therapy, susceptibility testing and AMS.

AMR/AMSSurveillance studyEurope

Diversity and host association of cfr-carrying plasmids of multidrug-resistant microorganisms from the Netherlands.

Journal International Journal of Antimicrobial Agents · First author Jansen TH · Country Netherlands · Study type Surveillance study

Key findings (from abstract)

Dutch plasmids linked to plasmids from China, Denmark, the United States, South-Korea, Germany and Poland. Across all Dutch plasmids, the cfr-gene was flanked by transposable elements. The diversity among cfr-carrying plasmids in unrelated Dutch surveillance isolates and their relatedness to plasmids from countries in different global regions suggest multiple independent introductions into the Netherlands, although horizontal dissemination by transposons may contribute to their spread.

FRCPath relevance

AMR/antimicrobial stewardship content relevant to FRCPath antimicrobial therapy, susceptibility testing and AMS.

AMR/AMSCase reportEurope

Therapeutic challenges in prosthetic valve Granulicatella adiacens endocarditis: a case report and focused review of alternative antimicrobial strategies.

Journal Diagnostic Microbiology and Infectious Disease · First author Reidy N · Country Ireland · Study type Case report

Key findings (from abstract)

Ceftriaxone-resistant PVIE was complicated by DRESS syndrome and linezolid-associated thrombocytopaenia. Treatment with ertapenem and levofloxacin was completed following surgery. Evidence supporting alternative treatment strategies for Granulicatella infections remains limited, highlighting the need for further research.

FRCPath relevance

AMR/antimicrobial stewardship content relevant to FRCPath antimicrobial therapy, susceptibility testing and AMS.

Vaccines1

VaccinesLetterEurope

Humoral immunity after mRNA SARS-CoV-2 XFG vaccination.

Journal The Lancet Infectious Diseases · First author Happle C · Country Germany · Study type Letter

Key findings (from abstract)

not stated (no abstract available in source record)

FRCPath relevance

Vaccinology content relevant to FRCPath immunisation and public-health microbiology.

Diagnostics1

DiagnosticsSurveillance study

Anti-HCV signal-to-cutoff ratio for predicting hepatitis C viremia in a hospital-based population and genotype distribution: A five-year single-center study.

Journal Diagnostic Microbiology and Infectious Disease · First author Şanda ZS · Country not stated · Study type Surveillance study

Key findings (from abstract)

Of 337,030 anti-HCV tests, 1,434 (0.42%) were reactive, and all were tested for HCV-RNA. Of these, 363 (0.11%) were viremic. Anti-HCV S/CO ratios predict the presence of viremia but not its magnitude. Furthermore, genotype 1b predominated in older age groups, while genotypes 4 and 5 were more frequently observed among patients of Syrian nationality.

FRCPath relevance

Laboratory diagnostics content relevant to FRCPath test evaluation, laboratory methods and quality.

Others1

Othersnot statedPreprint

Epstein-Barr virus influences the induction of protective antibody responses in young African children vaccinated with the RTS,S malaria vaccine

Journal medRxiv (preprint, not peer reviewed) · First author Harris, A. W. · Country not stated · Study type not stated

Key findings (from abstract)

We evaluated whether latent CMV/EBV infections impact RTS,S-induced antibodies in 314 vaccinated children aged 5-29 months in West Africa. While no strong associations were observed for CMV, children seropositive for EBV had lower antigen-specific IgG and IgA, which have been linked with protective malaria immunity. These results may partly explain why malaria vaccines are suboptimal in populations where early CMV/EBV infections are prevalent.

FRCPath relevance

Broader infection science/epidemiology; background reading for FRCPath.

Diagnostic Microbiology and Infectious Disease3

DiagnosticsSurveillance study

Anti-HCV signal-to-cutoff ratio for predicting hepatitis C viremia in a hospital-based population and genotype distribution: A five-year single-center study.

Journal Diagnostic Microbiology and Infectious Disease · First author Şanda ZS · Country not stated · Study type Surveillance study

Key findings (from abstract)

Of 337,030 anti-HCV tests, 1,434 (0.42%) were reactive, and all were tested for HCV-RNA. Of these, 363 (0.11%) were viremic. Anti-HCV S/CO ratios predict the presence of viremia but not its magnitude. Furthermore, genotype 1b predominated in older age groups, while genotypes 4 and 5 were more frequently observed among patients of Syrian nationality.

FRCPath relevance

Laboratory diagnostics content relevant to FRCPath test evaluation, laboratory methods and quality.

BacteriaProspective study

A parsimonious machine-learning model using routine laboratory data to differentiate nontuberculous mycobacterial disease from tuberculosis: Development and independent external validation.

Journal Diagnostic Microbiology and Infectious Disease · First author Zhang R · Country China · Study type Prospective study

Key findings (from abstract)

A post-hoc benchmark did not show an overall advantage for Extra Trees over other algorithms. Routine variables may help prioritize confirmatory testing, but the frozen threshold cannot support stand-alone diagnosis or exclusion of NTM. Prospective evaluation must verify patient-level measurement timing, reference diagnoses and clinical impact.

FRCPath relevance

Bacteriology content relevant to FRCPath Part 1/2 clinical bacteriology and pathogen-specific management.

AMR/AMSCase reportEurope

Therapeutic challenges in prosthetic valve Granulicatella adiacens endocarditis: a case report and focused review of alternative antimicrobial strategies.

Journal Diagnostic Microbiology and Infectious Disease · First author Reidy N · Country Ireland · Study type Case report

Key findings (from abstract)

Ceftriaxone-resistant PVIE was complicated by DRESS syndrome and linezolid-associated thrombocytopaenia. Treatment with ertapenem and levofloxacin was completed following surgery. Evidence supporting alternative treatment strategies for Granulicatella infections remains limited, highlighting the need for further research.

FRCPath relevance

AMR/antimicrobial stewardship content relevant to FRCPath antimicrobial therapy, susceptibility testing and AMS.

International Journal of Antimicrobial Agents3

AMR/AMSSurveillance studyEurope

Diversity and host association of cfr-carrying plasmids of multidrug-resistant microorganisms from the Netherlands.

Journal International Journal of Antimicrobial Agents · First author Jansen TH · Country Netherlands · Study type Surveillance study

Key findings (from abstract)

Dutch plasmids linked to plasmids from China, Denmark, the United States, South-Korea, Germany and Poland. Across all Dutch plasmids, the cfr-gene was flanked by transposable elements. The diversity among cfr-carrying plasmids in unrelated Dutch surveillance isolates and their relatedness to plasmids from countries in different global regions suggest multiple independent introductions into the Netherlands, although horizontal dissemination by transposons may contribute to their spread.

FRCPath relevance

AMR/antimicrobial stewardship content relevant to FRCPath antimicrobial therapy, susceptibility testing and AMS.

Journal of Infection3

Infection controlGenomic studyUK

The evolution of carbapenem-resistant Klebsiella pneumoniae in Greek intensive care units is driven by local carbapenemase acquisition, nationwide nosocomial spread and emerging resistance to novel antimicrobials.

Journal Journal of Infection · First author Baltas I · Country United Kingdom · Study type Genomic study

Key findings (from abstract)

All isolates produced carbapenemases: 48% KPC, 20% NDM, 4.4% VIM, 27.6% multi-carbapenemase producers. Resistance to carbapenems, fluoroquinolones, aminoglycosides, and co-trimoxazole exceeded 90%, except for amikacin (73.4%) and colistin (46.5%). In Greek ICUs, CR-Kp appears to emerge via local plasmid acquisition and then spread within and between hospitals. While aztreonam-avibactam and cefepime-zidebactam remain promising treatment options, resistance among multi-carbapenemase producers and diagnostic gaps (notably for VEB variants) are concerning.

FRCPath relevance

Infection prevention and control content relevant to FRCPath IPC and outbreak-management competencies.

AMR/AMSSurveillance study

Linezolid Minimum Inhibitory Concentration Creep and Precision Dosing in Older Adults: a longitudinal surveillance and multicentre population pharmacokinetic study.

Journal Journal of Infection · First author Liu T · Country China · Study type Surveillance study

Key findings (from abstract)

Among 506 isolates, geometric mean minimum inhibitory concentration (MIC) increased from 1.587 to 1.796mg/L; the proportion at 2mg/L increased from 69.2% to 82.2%, whereas values ≤ 1mg/L decreased from 30.8% to 16.7%. Pharmacokinetic analysis included 406 patients and 1,032 samples; age and eGFR influenced clearance. Linezolid MICs shifted towards 2mg/L, while age and eGFR contributed to exposure variability. MIC-informed model-informed precision dosing, early therapeutic drug monitoring, and haematological monitoring may help balance efficacy and toxicity.

FRCPath relevance

AMR/antimicrobial stewardship content relevant to FRCPath antimicrobial therapy, susceptibility testing and AMS.

The Journal of Infectious Diseases2

VirusSurveillance studyEurope

Viral Aetiology of Lower Respiratory Tract Infections in Infants Attending Primary Care in Eastern Spain, 2023-2025.

Journal The Journal of Infectious Diseases · First author Marcello-Carloni L · Country Italy · Study type Surveillance study

Key findings (from abstract)

To describe seasonal patterns of respiratory viruses in infants presenting to primary care (PC) after the rollout of the RSV-immunisation programme in Spain, we analysed multiplex RT-PCR results from infants <1 year with lower respiratory tract infections (LRTIs) attending 57 PC centres in Valencia and Murcia across two seasons. Among the 307 infants, rhinovirus/enterovirus and RSV were the most common detections in both periods. hMPV, bocavirus, and influenza followed. Our findings highlight the importance of community-based surveillance systems for providing real-world evidence to inform future immunisation strategies.

FRCPath relevance

Clinical virology content relevant to FRCPath virology/infection curricula (diagnosis, epidemiology, management).

Virusnot stated

Biological Sex as a Determinant of Neurological Outcomes During Zika Virus Infection.

Journal The Journal of Infectious Diseases · First author Mansour A · Country Canada · Study type not stated

Key findings (from abstract)

Given that many viral infections can lead to long-term neurological complications, it is crucial to understand how biological sex influences neuroinflammation. Using a mouse model of Zika virus infection, we find that males develop more severe clinical disease compared to females, despite comparable infectious viral loads. Our findings demonstrate that sexually dimorphic immune responses contribute to increased male susceptibility to virus-induced neuropathology.

FRCPath relevance

Clinical virology content relevant to FRCPath virology/infection curricula (diagnosis, epidemiology, management).

The Lancet Infectious Diseases2

VirusReviewUK

Combination antiviral treatment for a patient with lymphocytic choriomeningitis virus meningoencephalitis associated with bispecific antibody teclistamab therapy for myeloma.

Journal The Lancet Infectious Diseases · First author Maamari RG · Country United Kingdom · Study type Review

Key findings (from abstract)

The patient regained functional independence and returned to work, with only mild residual symptoms. In addition to reporting a novel occurrence of LCMV infection in a patient on teclistamab, the case highlights the presence of LCMV in the UK and the utility of metagenomic next-generation sequencing for pathogen identification in undiagnosed encephalitis. Finally, the case provides preliminary evidence supporting combination antiviral therapy in persistent LCMV infection.

FRCPath relevance

Clinical virology content relevant to FRCPath virology/infection curricula (diagnosis, epidemiology, management).

VaccinesLetterEurope

Humoral immunity after mRNA SARS-CoV-2 XFG vaccination.

Journal The Lancet Infectious Diseases · First author Happle C · Country Germany · Study type Letter

Key findings (from abstract)

not stated (no abstract available in source record)

FRCPath relevance

Vaccinology content relevant to FRCPath immunisation and public-health microbiology.

medRxiv (preprint, not peer reviewed)2

BacteriaSystematic reviewPreprint

Vitamin D supplementation to prevent tuberculosis infection and disease: systematic review and individual participant data meta-analysis of randomised controlled trials

Journal medRxiv (preprint, not peer reviewed) · First author Jolliffe, D. A. · Country not stated · Study type Systematic review

Key findings (from abstract)

Four trials contributed IPD for 14,619 participants. Vitamin D did not reduce risk of incident tuberculosis infection (9,557 participants; aOR 0.97, 95% CI 0.81-1.18; p=0.79) or incident tuberculosis disease (14,533 participants; aOR 0.78, 95% CI 0.56-1.10; p=0.15). Vitamin D supplementation did not reduce the risk of incident tuberculosis infection or disease in the populations studied, either overall or within sub-groups. The 95% confidence interval of the effect estimate for prevention of tuberculosis disease remains compatible with a potentially important benefit, and further trials for this indication may be warranted.

FRCPath relevance

Bacteriology content relevant to FRCPath Part 1/2 clinical bacteriology and pathogen-specific management.

Othersnot statedPreprint

Epstein-Barr virus influences the induction of protective antibody responses in young African children vaccinated with the RTS,S malaria vaccine

Journal medRxiv (preprint, not peer reviewed) · First author Harris, A. W. · Country not stated · Study type not stated

Key findings (from abstract)

We evaluated whether latent CMV/EBV infections impact RTS,S-induced antibodies in 314 vaccinated children aged 5-29 months in West Africa. While no strong associations were observed for CMV, children seropositive for EBV had lower antigen-specific IgG and IgA, which have been linked with protective malaria immunity. These results may partly explain why malaria vaccines are suboptimal in populations where early CMV/EBV infections are prevalent.

FRCPath relevance

Broader infection science/epidemiology; background reading for FRCPath.

The Lancet Microbe1

American Journal of Infection Control0

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Antimicrobial Agents and Chemotherapy0

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Antimicrobial Resistance & Infection Control0

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Clinical Infectious Diseases0

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Clinical Microbiology Reviews0

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Clinical Microbiology and Infection0

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Emerging Infectious Diseases0

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European Journal of Clinical Microbiology & Infectious Diseases0

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Infection Control & Hospital Epidemiology0

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Infection Prevention in Practice (IPIP)0

No new records from this journal in today’s window.

JAC-Antimicrobial Resistance0

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Journal of Antimicrobial Chemotherapy0

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Journal of Clinical Microbiology0

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Journal of Clinical Virology0

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Journal of Hospital Infection0

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Journal of Infection Prevention0

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Journal of Medical Microbiology0

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Medical Mycology0

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Nature Microbiology0

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Open Forum Infectious Diseases0

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mBio0

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Sources searched27 journals + medRxiv

Window: PubMed Entrez date 05 Nov – 06 Nov 2026; medRxiv first publication date 05 Nov – 06 Nov 2026. Papers already listed in earlier issues are excluded. All queries succeeded.

SourceAbbrev.ViaPapers today
Journal of InfectionJ InfectPubMed3
The Lancet Infectious DiseasesLancet Infect DisPubMed2
Clinical Infectious DiseasesClin Infect DisPubMed0
The Journal of Infectious DiseasesJ Infect DisPubMed2
Clinical Microbiology and InfectionClin Microbiol InfectPubMed0
Open Forum Infectious DiseasesOpen Forum Infect DisPubMed0
Emerging Infectious DiseasesEmerg Infect DisPubMed0
Clinical Microbiology ReviewsClin Microbiol RevPubMed0
Journal of Clinical MicrobiologyJ Clin MicrobiolPubMed0
The Lancet MicrobeLancet MicrobePubMed1
Journal of Medical MicrobiologyJ Med MicrobiolPubMed0
Nature MicrobiologyNat MicrobiolPubMed0
mBiomBioPubMed0
Diagnostic Microbiology and Infectious DiseaseDiagn Microbiol Infect DisPubMed3
European Journal of Clinical Microbiology & Infectious DiseasesEur J Clin Microbiol Infect DisPubMed0
Journal of Hospital InfectionJ Hosp InfectPubMed0
Infection Prevention in Practice (IPIP)Infect Prev PractPubMed0
Infection Control & Hospital EpidemiologyInfect Control Hosp EpidemiolPubMed0
American Journal of Infection ControlAm J Infect ControlPubMed0
Antimicrobial Resistance & Infection ControlAntimicrob Resist Infect ControlPubMed0
Journal of Infection PreventionJ Infect PrevPubMed0
Journal of Antimicrobial ChemotherapyJ Antimicrob ChemotherPubMed0
Antimicrobial Agents and ChemotherapyAntimicrob Agents ChemotherPubMed0
International Journal of Antimicrobial AgentsInt J Antimicrob AgentsPubMed3
JAC-Antimicrobial ResistanceJAC Antimicrob ResistPubMed0
Journal of Clinical VirologyJ Clin VirolPubMed0
Medical MycologyMed MycolPubMed0
medRxiv (infectious-disease preprints)via Europe PMCEurope PMC2
Total16
Generated 2026-11-06 with build_jw.py. Sources: NCBI PubMed E-utilities; Europe PMC REST API.
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