Parasitology treatment – aide-memoire

Acanthamoeba

Keratitis:
Polyhexanide (PHMB) 0.02%
Chlorhexidine 0.02% (+/- Brolene 0.1%)
Propamidine (0.1%) or
hexamidine (0.1%)
Imidazole, neomycin,
NSAID, prednisolone.
(Ref: Acanthamoeba Keratitis Treatment, AAO; Focus, Autumn 2013, RCOphth)
Granulomatous amoebic encephalitis:
The optimum treatment is unknown. A combination of drugs has been used – cotrimoxazole, metronidazole, pentamidine, miltefosine, and fluconazole.
Other drugs with activity – Azithromycin, rifampicin, voriconazole, flucytosine, caspofungin etc.
Cutaneous lesion:
Optimum treatment is unknown. Drugs used-
Topical chlorhexidine, ketoconazole cream,
Pentamidine, Itraconazole, voriconazole, liposomal amphotericin B, flucytosine, miltefosine etc read more