Daptomycin

Class: Cyclic lipopeptide Source: Streptomyces roseosporus Discovered: 1980s; approved for use in 2003 (FDA) Molecular weight: 1620 DA. Immunomodulatory effect: Daptomycin causes limited/no bacterial cell lysis. It also impairs the cell division. This process leads to...

MCQ Mixed set 2

0 Mixed set 2 1 / 10 Pivmecillinam has a high affinity for ______ of E coli. PBP1a PBP2 PBP3 PBP4 PBP5 PBP1a - cefuroxime, cefotaxime, benzylpenicillinPBP2 - mecillinam, clavulinic acid, imipenemPBP3 - cefalexin, piperacillin, moxalactam, mezlocillin, aztreonamPBP4 -...
Adenovirus

Adenovirus

Non-enveloped linear ds-DNA virus. Icosahedral symmetry (70-90 nm diameter). The capsid has three major protein – hexon, penton, and fibre. Adenovirus is being investigated as a vector for vaccine and gene therapy. Ubiquitous in nature. Most people are...
Cefiderocol

Cefiderocol

Class and Chemical structure: Siderophore cephalosporin.  It is a synthetic conjugate, of a cephalosporin moiety and a siderophore moiety. Siderophore moiety bind to the iron and helps the antibiotic to gain entry into bacterial cells using active iron transporters...
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